Characterization of a genetic element carrying the macrolide efflux gene mef(A) in Streptococcus pneumoniae.

نویسندگان

  • M Santagati
  • F Iannelli
  • M R Oggioni
  • S Stefani
  • G Pozzi
چکیده

The mef(A) gene from a clinical isolate of Streptococcus pneumoniae exhibiting the M-type resistance to macrolides was found to be part of the 7,244-bp chromosomal element Tn1207.1, which contained 8 open reading frames. orf2 encodes a resolvase/invertase, and orf5 is a homolog of the macrolide-streptogramin B resistance gene msr(SA).

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 44 9  شماره 

صفحات  -

تاریخ انتشار 2000